Also called: 5-amino-1-methylquinolinium, NNMT inhibitor, 1MQ
5-Amino-1MQ is a small chemical compound used in research to study how the body burns fat and makes energy. It is not a protein, but it is often grouped with research peptides. It works by blocking a specific enzyme in the body called NNMT. Scientists study it to see how stopping this enzyme changes metabolism.
It is usually sold as a research chemical and is not approved by health groups for everyday use.Researchers are interested in this compound because it might help lower body fat and build muscle. By blocking the NNMT enzyme, it is thought to speed up how fast cells use energy. This process could help researchers understand new ways to treat obesity and metabolic problems. Some early tests show it helps cells burn more calories, but most of this information comes from laboratory experiments.There is no proof yet that this compound is safe or works well in humans.
Most of the testing has been done in labs or on animals, not on people. Because it is sold strictly for research, it is not meant to be eaten or used as a medicine by anyone. Buyers should know that it lacks official approval from groups like the FDA. Anyone handling it must be very careful and treat it as an unapproved lab chemical.
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For research purposes only. Not medical advice. Talk to a doctor before use.
Compare research-grade suppliers with third-party COAs and published purity data. For in-vitro and laboratory research use only — not for human consumption, diagnosis, or treatment.
Neelakantan et al., Sci Rep / preclinical (referenced via PMC) 5-amino-1MQ NNMT inhibition, mouse DIO model
Pissios, Trends Endocrinol Metab (2017) NNMT in metabolic disease
Kraus et al., Nature (2014) Nicotinamide N-methyltransferase as a metabolic switch
Inhibition of NNMT increases NAD+ levels
NNMT inhibition plus lean-diet (Sampson et al., 2021)
NNMT knockdown reduces fat mass (Kraus et al., 2014)
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