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Selank

Also called: TP-7

By The Health Stacks Research TeamUpdated July 28, 2026

Selank is a synthetic heptapeptide used for anxiolytic and nootropic research.

Research-stageEarly-stage — studied in cell or animal models, not yet tested in humans. Medium confidence40–59 — backed by moderate-quality sources. Worth a closer look at the individual citations.
Where to Source Selank
Tested purity COA available Fast shipping

What Selank Helps With

The benefits people report — backed by research.

Neuroprotection & cognitive (31)

Anxiolytic 85/100· 2 srcSpeeds recovery 90/100Anxiolytic activity without sedation or addiction potential 85/100Supports brain health 85/100Anxiolytic effect comparable to medazepam without sedation 85/100Anxiolytic activity 85/100Enkephalinase inhibition 85/100Anxiolytic efficacy comparable to medazepam without sedation or dependence 85/100Reduces anxiety without sedation or dependence risk 85/100Anxiolytic effects comparable to benzodiazepines without sedation 85/100Anxiolytic without sedation or dependence 85/100Reduction in generalized anxiety disorder and neurasthenia symptoms 85/100Reduces anxiety without sedation 85/100Neuroprotection in ischemic stroke 85/100Stress Reduction 80/100Anxiolytic effect 80/100Increases BDNF mRNA expression 80/100Stabilization of enkephalin systems under stress conditions 80/100Dopaminergic sensitization 80/100Mood Regulation 75/100Anxiolytic effects without benzodiazepine side effects 75/100Protects against ethanol-induced memory impairment 75/100Nootropic support under stress 75/100Anxiolytic-like behavior 75/100Reduction in generalized anxiety disorder symptoms 75/100Stabilization of enkephalin systems 75/100Anxiolytic effects without sedation, amnesia, or dependence 72/100Neuroprotection 70/100Inhibition of enkephalin-degrading enzymes 70/100Enhancement of memory consolidation and attention via BDNF-mediated long-term potentiation 70/100Enhanced memory and learning 60/100

Immune modulation (6)

Immunomodulation 85/100Immunomodulation / Antiviral 85/100Strengthens immunity 80/100Immunomodulatory activity 80/100Antiviral / Immunomodulatory 75/100Immunomodulatory effects 75/100

Musculoskeletal (3)

Stress protection 85/100Stress Resilience / Corticosterone Regulation 75/100Anxiolytic activity via allosteric GABA-A receptor modulation without sedative effects 75/100

Cytoprotection / cellular defense (2)

No Tolerance Development 85/100Favorable preclinical safety profile with no documented tolerance or dependence 65/100

Cardiovascular & vascular (2)

Neuroprotection in stroke/ischemia 85/100Neuroprotection 80/100

Anti-inflammatory (2)

Strengthens immunity 80/100Immunomodulation 80/100

Other Benefits (4)

HPA Axis Normalisation 85/100Metabolic regulation 80/100Anti-ulcer effects 75/100Neuroprotection under oxidative stress by inhibiting enkephalin-degrading enzymes 65/100
Selank — cognitive

How People Use It

Under the skin

  • Injection (specific dose not listed in abstract)

For research purposes only. Not medical advice. Talk to a doctor before use.

Get Selank for Your Research

Compare research-grade suppliers with third-party COAs and published purity data. For in-vitro and laboratory research use only — not for human consumption, diagnosis, or treatment.

Find Selank Research Suppliers
Tested purity COA available Fast shipping
Technical Details & Research (click to expand)

Known Side Effects

All Dosing Protocols

Functional Connectivity Study — SubQ 95/100

Research Citations (43)

  • Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats

    2017 90/100
    Source

  • Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity

    90/100
    Source

  • Semax and selank inhibit the enkephalin-degrading enzymes from human serum

    90/100
    Source

  • Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo

    90/100
    Source

  • Optimization of the treatment of anxiety disorders with selank

    90/100
    Source

  • Physiological Effects of Selank and Its Fragments

    90/100
    Source

  • Selank upregulates hippocampal BDNF and NGF after a single intranasal dose

    85/100
    Source

  • Randomized 14-day trial showed anxiolytic efficacy comparable to medazepam without sedation, tolerance, or rebound

    85/100
    Source

  • Effects of Selank on Behavioral Reactions and Activities of Plasma Enkephalin-Degrading Enzymes in Mice with Different Phenotypes of Emotional and Stress Reactions

    85/100
    Source

  • Anxiolytic effect of an analog of taftsin (Selank)

    90/100
    Source

  • Selank: specific anxiolytic action and effects on brain monoamines

    90/100
    Source

  • Anxiolytic activity of Selank

    90/100
    Source

  • Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents

    90/100
    Source

  • The optimizing action of the synthetic peptide Selank on a conditioned active avoidance reflex in rats

    90/100
    Source

  • Effectiveness of semax in acute period of hemispheric ischemic stroke

    90/100
    Source

History & Milestones

Key moments in Selank’s research and regulatory timeline — sourced and dated.

  1. Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in RatsPublicationJan 1, 2017
    90/100↗ source

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