Selank
Shop SelankAlso called: TP-7, Selank Semax Peptide Stack, Semax and Selank Combination
Selank is a small man-made substance that researchers are studying to see how it affects the brain. It is a type of compound called a peptide, which is like a very short piece of protein. Scientists made it to copy a part of a natural body chemical that helps the brain work. It is mostly looked at by experts in a lab setting to learn about brain health and how we handle stress.
The main reason researchers look at Selank is for its possible effect on mood and worry. Studies suggest it might help calm the mind and reduce feelings of fear or nervousness. It works by interacting with the systems in the brain that control how we feel emotions. Some research also shows it might help with learning and memory, making it a subject of interest for brain health.
While it shows promise in early studies, Selank is not a proven medicine for people yet. Most of the research so far has been done on animals or in small test settings, so we do not know all the long-term effects. It is important to know that it is made for research only and is not checked by health groups for regular use. Scientists are still working to understand exactly how safe and effective it is for humans.
Regulatory status
Selank is an approved medicine in Russia for generalized anxiety and stress-related disorders; it is not approved by the US FDA or the EMA. It is not on the FDA's Section 503A Bulks List, remains an unapproved new drug under the FD&C Act, and cannot lawfully be compounded by traditional 503A pharmacies in the US.
Benefits
What Selank Helps With
The main themes across 25 research studies, in plain language.
Neuroprotection & cognitive
Anxiety reduction without sedation
50/100Rated 50/100Source typeUnclassified sourceIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 26 underlying claimsResearch suggests potential for reducing anxiety symptoms without the sedation, dependence, or cognitive impairment often associated with standard medications.
Cognitive enhancement & memory
85/100Rated 85/100Source typePeer-reviewed studyIndependent sources4Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 22 underlying claimsStudies indicate potential benefits for memory consolidation, learning, and attention, possibly through the regulation of neurotrophic factors.
Stress response regulation
60/100Rated 60/100Source typeSpecialist communityIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 12 underlying claimsEvidence suggests the peptide may help stabilize the body's stress response systems, including the HPA axis and enkephalin levels.
Neuroprotection & brain repair
40/100Rated 40/100Source typeVendor / seller pageIndependent sources4Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 12 underlying claimsPreclinical studies indicate potential protective effects for brain tissue, including support for recovery after ischemic stroke and upregulation of neurotrophic factors.
General neuropeptide signaling
40/100Rated 40/100Source typeUnclassified sourceIndependent sources4Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 6 underlying claimsResearch includes the investigation of basic neuropeptide signaling pathways and peptide stability.
Mood & emotional regulation
85/100Rated 85/100Source typePeer-reviewed studyIndependent sources4Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 5 underlying claimsResearch suggests a potential role in stabilizing mood and alleviating symptoms of depression or neurasthenia.
Neurotransmitter system support
60/100Rated 60/100Source typeSpecialist communityIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 4 underlying claimsEvidence indicates the ability to modulate key neurotransmitters, such as serotonin and dopamine, and influence GABA receptor activity.
Safety & tolerance profile
40/100Rated 40/100Source typeVendor / seller pageIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 3 underlying claimsPreclinical data suggests a favorable safety profile with no evidence of tolerance development or dependence risk.
Gastrointestinal mucosal protection
72/100Rated 72/100Source typeEstablished referenceIndependent sources1Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 1 underlying claimSome studies have investigated potential protective effects against gastric ulcers.
Immune system modulation
60/100Rated 60/100Source typeSpecialist communityIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 16 underlying claimsResearch points to a role in balancing immune responses, including the modulation of cytokines like interferon-alpha and IL-6.
Antiviral activity research
72/100Rated 72/100Source typeEstablished referenceIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 3 underlying claimsStudies have explored potential antiviral properties, specifically in the context of H3N2 influenza.
Metabolic & glycemic regulation
72/100Rated 72/100Source typeEstablished referenceIndependent sources3Every claim links to the page it came from, and stronger sources rate higher. Full methodology →· 2 underlying claimsInitial research explores the impact on metabolic processes, including hemostasis and lipid/glucose regulation.
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How People Use It
1 reported routine — each line links to the source it came from.
From published sources
Routines as reported in peer-reviewed papers, clinical guidance, or vetted media — each linked to the source it came from.
SubQ
- Selank: 200–300 mcg; Semax: 200–400 mcg 85/100Rated 85/100Source typePeer-reviewed studyIndependent sources1Every claim links to the page it came from, and stronger sources rate higher. Full methodology →↗ source
mg vs mcg: one milligram (mg) equals 1,000 micrograms (mcg) — multiply by 1,000 going from mg to mcg, divide by 1,000 going from mcg to mg. Mixing the two up is a thousand-fold dosing error: 1 mg taken instead of 1 mcg is a 1,000× overdose; 1 mcg instead of 1 mg is a 1,000× underdose. Always double-check the unit label and the decimal place.
Safety
Known Side Effects
Adverse effects reported in the research and by community use.
- Sleep disruptionMild 60/100Rated 60/100Source typeSpecialist communityIndependent sources1Every claim links to the page it came from, and stronger sources rate higher. Full methodology →↗ peptidepedia.org
- Transient anxietyMild 60/100Rated 60/100Source typeSpecialist communityIndependent sources1Every claim links to the page it came from, and stronger sources rate higher. Full methodology →↗ peptidepedia.org
Reported in research and community sources — not exhaustive. Discontinue use and consult a healthcare professional if side effects occur.
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Evidence
Research Citations (17)
Every claim above traces back to a source you can check — here are 17 of them.
- Source
Selank | C33H57N11O9 | CID 11765600 - PubChem
95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
PubChem - Compound - Selank
95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Immunomodulatory effects of selank in patients with anxiety-asthenic disorders
2008 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Effects of heptapeptide selank on the content of monoamines and their metabolites in the brain of BALB/C and C57Bl/6 mice: a comparative study
2008 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Experimental optimization of learning and memory processes by selank
2010 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Comparison of the effects of selank and tuftsin on the metabolism of serotonin in the brain of rats pretreated with PCPA
2009 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo.
2008 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Semax and selank inhibit the enkephalin-degrading enzymes from human serum]
2001 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Effect of selank on the main carboxypeptidases in the rat nervous tissue
2012 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Effects of heptapeptide selank on genetically-based and situation-provoked symptoms of depression in behavior in WAG/Rij and Wistar rats, and in BALB/c mice
2008 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia
2008 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats
2019 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
COMPARISON OF PHARMACOLOGICAL EFFECTS OF HEPTAPEPTIDE SELANK AFTER INTRANASAL AND INTRAPERITONEAL ADMINISTRATION TO BALB/c AND C57BL/6 MICE.
95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
PubChem - Compound - Selank acetate
95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Search Page
95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology →
Timeline
History & Milestones
Key moments in Selank’s research and regulatory timeline — sourced and dated.
- Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in RatsPublicationJan 1, 2017Related:Selank
News
Latest on Selank
Dated, sourced reporting that mentions Selank.
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