CJC-1295 vs Ipamorelin
Two growth-hormone secretagogues often studied together — a GHRH analog vs a GHRP. Here's a neutral, sourced side-by-side — no hype, every claim links to its evidence.
CJC-1295
ApprovedAlso: CJC 1295, mod GRF 1-29
CJC-1295 is a man-made chemical messenger. It is a short chain of building blocks that tell your body to make more of its own growth hormone.
Ipamorelin
ResearchAlso: GHRP, Ipamorelin and CJC-1295
Ipamorelin is a man-made peptide, which is a tiny chain of building blocks called amino acids. It is a copy of a natural body chemical called ghrelin, which is sometimes called the hunger hormone.
At a Glance
| CJC-1295 | Ipamorelin | |
|---|---|---|
| Research status | Approved | Preclinical |
| Highest-tier evidence | Peer-reviewed study | Peer-reviewed study |
| Research citations | 8 | 8 |
| Dosing routes | SubQ | — |
| Receptor targets | GHRH receptor | GHS-R (ghrelin receptor) |
| Half-life | ~6-8 days (with DAC, albumin-bound); minutes-to-hours withou | — |
| Known side effects | 18 | 9 |
Research Areas
Top preclinical research areas — cited studies for each.
CJC-1295
- Sustained GH elevation
- Sustained IGF-1 elevation
Ipamorelin
- Stimulates GH release
- Selective (minimal cortisol)
How People Use It
Reported routines — research only, not medical advice.
CJC-1295
- SubQ — CJC-1295: 50-100 mcg; Ipamorelin: 100-200 mcg
- SubQ — 100 mcg CJC-1295 + 100-200 mcg Ipamorelin
Ipamorelin
- — 100–250 mcg once daily SC (research: 100–300 mcg 2–3×/day)
The Evidence
Key studies — click through to verify each on PubMed.
CJC-1295
8 sourced studies
- Source
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
RCT2006 Key study 86/100Rated 86/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects.
AnimalStudy2009 80/100Rated 80/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog.
95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.
2006 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology →
Ipamorelin
8 sourced studies
- Source
Ipamorelin, the first selective growth hormone secretagogue.
AnimalStudy1998 Key study 84/100Rated 84/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Ipamorelin for post-operative ileus (NCT00672074)
Registry2014 78/100Rated 78/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers.
1999 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology → - Source
Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats.
1999 95/100Rated 95/100Source typePeer-reviewed studyIndependent sourcesstill being verifiedEvery claim links to the page it came from, and stronger sources rate higher. Full methodology →
Decision Guide
How to Choose
Neither is a “winner” — they suit different goals. Compare the documented benefits and evidence above against what you’re actually trying to achieve, note the research status (approved vs research-stage), and read each full guide before deciding. Many people also stack peptides rather than pick one.
Source CJC-1295
Shop CJC-1295Source Ipamorelin