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Lilly's selective amylin agonist, eloralintide, demonstrated meaningful weight loss and favorable tolerability in a Phase 2 study of adults with obesity or overweight

Clinical 60/100
July 28, 2026↗ source

Eli Lilly announced positive Phase 2 results for eloralintide, a selective amylin receptor agonist, showing placebo-adjusted weight loss ranging from 9.1% to 19.7% over 48 weeks. The drug demonstrated a favorable tolerability profile and improvements in cardiometabolic markers. Based on these data, Lilly plans to initiate Phase 3 trials for obesity treatment next month.

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